CBLN4

Across TCGA cell cohorts, CBLN4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CBLN4-associated genes across cancer lineages are KRT28, OR10Q1, and TEX33. Each is linked with CBLN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLN4-to-partner and partner-to-CBLN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT28 grouped by CBLN4-low versus CBLN4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN4→partner) and Y-score (partner→CBLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRT28 →	+0.006	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR10Q1 →	+0.073	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.027	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	ANKRD34C →	+0.062	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KRT28 by CBLN4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →