CBLN3

Across TCGA patient cohorts, CBLN3 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBLN3-associated genes across cancer lineages are RNU6-1318P, MAPK13, and RNU6-776P. Each is linked with CBLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLN3-to-partner and partner-to-CBLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by CBLN3-low versus CBLN3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN3→partner) and Y-score (partner→CBLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1318P →	+0.471	+5.292	<.001	.006	3	2
UCEC	MAPK13 →	+0.758	+3.332	.004	.005	3	1
BRCA	RNU6-776P →	+0.282	+8.471	<.001	.005	3	1
BRCA	MIR525 →	+0.561	+7.731	<.001	.009	3	1
BRCA	RNU6-278P →	+0.272	+7.731	<.001	.009	3	1
BRCA	MIR1197 →	+0.467	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

RNU6-1318P by CBLN3 expression — SKCM

Explore this box plot interactively →