CBLN3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CBLN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,196 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CBLN3-associated GO terms across cancer lineages are Regulation of stress-activated MAPK cascade, Macroautophagy, and Response to starvation. Each is linked with CBLN3 in more than 11 cancer types. Because this analysis shows association rather than direction, both CBLN3-to-partner and partner-to-CBLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of stress-activated MAPK cascade grouped by CBLN3-low versus CBLN3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN3→partner) and Y-score (partner→CBLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaRegulation of stress-activated MAPK cascade →+0.078+1.010<.001.006312
UPPER_AERODIGESTIVE_TRACTMacroautophagy →+0.083+1.368<.001<.001311
LUNG_SCLCResponse to starvation →+0.052+0.572.001.002310
UPPER_AERODIGESTIVE_TRACTProcess utilizing autophagic mechanism →+0.046+0.891<.001<.001310
BLOOD_LymphomaRetrograde transport, endosome to Golgi →+0.065+1.452<.001<.001310
UPPER_AERODIGESTIVE_TRACTAutophagy →+0.046+0.891<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,196 associations by consensus.

Regulation of stress-activated MAPK cascade by CBLN3 expression — BLOOD_Lymphoma

Box plot of Regulation of stress-activated MAPK cascade in CBLN3-low vs CBLN3-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration