CBLN3

Across TCGA cell cohorts, CBLN3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible CBLN3-associated genes across cancer lineages are SLC5A8 and KRTAP12-3. Each is linked with CBLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLN3-to-partner and partner-to-CBLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A8 grouped by CBLN3-low versus CBLN3-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN3→partner) and Y-score (partner→CBLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SLC5A8 by CBLN3 expression — OESOPHAGUS

Explore this box plot interactively →