CBLN2

Across TCGA cell cohorts, CBLN2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CBLN2-associated genes across cancer lineages are PRAMEF10, TBC1D3, and CD300H. Each is linked with CBLN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLN2-to-partner and partner-to-CBLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF10 grouped by CBLN2-low versus CBLN2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN2→partner) and Y-score (partner→CBLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRAMEF10 →	+0.012	+4.662	<.001	.005	3	1
LARGE_INTESTINE	TBC1D3 →	+0.088	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PRAMEF10 by CBLN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →