CBLL2

Across TCGA patient cohorts, CBLL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,768 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CBLL2-associated GO terms across cancer lineages are Protein stabilization, Positive regulation of translation, and Arp2/3 complex-mediated actin nucleation. Each is linked with CBLL2 in more than 13 cancer types. Because this analysis shows association rather than direction, both CBLL2-to-partner and partner-to-CBLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by CBLL2-low versus CBLL2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLL2→partner) and Y-score (partner→CBLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein stabilization →	+0.079	+0.127	<.001	.001	3	14
ESCA	Positive regulation of translation →	+0.082	+0.101	<.001	.002	3	14
STAD	Arp2/3 complex-mediated actin nucleation →	+0.073	+0.099	<.001	<.001	3	13
STAD	Regulation of RNA splicing →	+0.084	+0.092	<.001	<.001	3	13
ESCA	Glucan biosynthetic process →	+0.056	+0.104	<.001	.002	3	13
STAD	Regulation of organelle assembly →	+0.071	+0.095	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,768 associations by consensus.

Protein stabilization by CBLL2 expression — ESCA

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