CBLB

Across TCGA patient cohorts, CBLB protein abundance is significantly associated with the RNA expression of many other genes, with 5,365 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CBLB-associated genes across cancer lineages are PALM2AKAP2, GTF2E1, and RNU6-353P. Each is linked with CBLB in more than 3 cancer types. Because this analysis shows association rather than direction, both CBLB-to-partner and partner-to-CBLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBLB versus PALM2AKAP2 in COAD, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLB→partner) and Y-score (partner→CBLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PALM2AKAP2 →	+0.578	+0.401	.001	.001	3	3
OV	GTF2E1 →	+0.397	+0.297	.002	.003	2	4
UCEC	RNU6-353P →	-1.414	-0.331	<.001	<.001	3	3
HNSC	PRKCB →	+0.498	+0.156	.001	.006	3	3
LSCC	ALDH5A1 →	-0.733	-0.289	<.001	<.001	3	3
HNSC	HRH2 →	+0.502	+0.202	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,365 associations by consensus.

CBLB vs PALM2AKAP2 — COAD

Explore this scatter interactively →