CBL

Across TCGA patient cohorts, CBL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,143 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CBL-associated proteins across cancer lineages are CUL5, FAM76B_S193, and UBE4A. Each is linked with CBL in more than 3 cancer types. Because this analysis shows association rather than direction, both CBL-to-partner and partner-to-CBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBL versus CUL5 in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBL→partner) and Y-score (partner→CBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CUL5 →	+0.202	+0.382	<.001	<.001	3	4
LSCC	FAM76B_S193 →	+0.427	+0.387	<.001	<.001	3	4
LUAD	UBE4A →	+0.198	+0.361	<.001	<.001	3	4
LSCC	RBMX2 →	+0.391	+0.499	<.001	<.001	3	4
CCRCC	KIF7_S895 →	+0.672	+0.470	<.001	<.001	3	4
PDAC	HID1 →	-0.606	-0.420	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,143 associations by consensus.

CBL vs CUL5 — HNSC

Explore this scatter interactively →