CBFB

Across TCGA patient cohorts, CBFB protein abundance is significantly associated with the RNA expression of many other genes, with 12,617 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CBFB-associated genes across cancer lineages are CMTM1, IL21R, and CHST11. Each is linked with CBFB in more than 6 cancer types. Because this analysis shows association rather than direction, both CBFB-to-partner and partner-to-CBFB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBFB versus CMTM1 in PDAC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBFB→partner) and Y-score (partner→CBFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CMTM1 →	+0.578	+0.264	<.001	<.001	3	7
UCEC	IL21R →	+0.943	+0.276	<.001	<.001	3	6
LSCC	CHST11 →	+0.715	+0.252	<.001	<.001	3	6
UCEC	CD80 →	+0.828	+0.291	.001	<.001	3	6
BRCA	CSF2RB →	+1.228	+0.353	.002	.003	3	5
BRCA	HCK →	+0.798	+0.313	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,617 associations by consensus.

CBFB vs CMTM1 — PDAC

Explore this scatter interactively →