CAVIN3

Across TCGA pan-cancer cohorts, CAVIN3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CAVIN3 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CAVIN3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CAVIN3 expression acts as an unfavorable survival marker.

LSCC, GBM, and LUAD are the cancer types where CAVIN3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.830	1.000	.003	25	view →
GBM	DFS	Quartile	All	0.597	0.881	.005	22	view →
LUAD	DFS	Median	II,III,IV	0.671	0.985	.003	22	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	4	view →
HNSC	DFS	Quartile	II,III,IV	0.510	0.793	.016	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CAVIN3–LSCC (DFS)

Open the LSCC breakdown →