CAVIN2-AS1

Across TCGA pan-cancer cohorts, CAVIN2-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CAVIN2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CAVIN2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CAVIN2-AS1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KIRP, KICH, and LUSC are the cancer types where CAVIN2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAVIN2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	+0.583	<.001	11	view →
KICH	All	All	−0.062	<.001	10	view →
LUSC	Female	All	−0.303	<.001	9	view →
STAD	All	All	−0.133	<.001	9	view →
BLCA	Male	All	−0.162	.001	8	view →
KIRC	All	All	+0.086	<.001	8	view →
THCA	Female	II,III,IV	−0.778	<.001	7	view →
BRCA	All	III,IV	−0.374	<.001	6	view →
COAD	All	All	−0.036	.001	4	view →
LUAD	Female	II,III,IV	−0.187	.001	3	view →
PRAD	All	All	+0.322	.007	2	view →
READ	All	All	−0.078	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CAVIN2-AS1–KIRP

Open the KIRP breakdown →