CAVIN1

Across TCGA cell cohorts, CAVIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,956 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CAVIN1-associated GO terms across cancer lineages are Positive regulation of actin filament bundle assembly, Regulation of cell-substrate adhesion, and Positive regulation of cell-substrate adhesion. Each is linked with CAVIN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CAVIN1-to-partner and partner-to-CAVIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of actin filament bundle assembly grouped by CAVIN1-low versus CAVIN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAVIN1→partner) and Y-score (partner→CAVIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of actin filament bundle assembly →	+0.198	+3.239	<.001	<.001	3	16
BONE	Regulation of cell-substrate adhesion →	+0.138	+3.700	<.001	<.001	3	15
BONE	Positive regulation of cell-substrate adhesion →	+0.163	+3.639	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	+1.772	+4.443	<.001	<.001	3	15
BONE	Positive regulation of cell-substrate junction organization →	+0.188	+3.543	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.111	+4.363	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,956 associations by consensus.

Positive regulation of actin filament bundle assembly by CAVIN1 expression — BONE

Explore this box plot interactively →