CAVIN1

Across TCGA cell cohorts, CAVIN1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAVIN1-associated genes across cancer lineages are MBD3L3, FABP12, and CST9. Each is linked with CAVIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAVIN1-to-partner and partner-to-CAVIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MBD3L3 grouped by CAVIN1-low versus CAVIN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAVIN1→partner) and Y-score (partner→CAVIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MBD3L3 →	+0.023	+3.874	.001	.005	3	2
LARGE_INTESTINE	FABP12 →	+0.041	+3.217	<.001	.006	3	2
BLOOD_Lymphoma	CST9 →	+0.060	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Leukemia	GHRHR →	+0.370	+3.705	<.001	.007	3	1
BLOOD_Leukemia	OR1N1 →	+0.079	+4.234	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

MBD3L3 by CAVIN1 expression — BLOOD_Leukemia

Explore this box plot interactively →