CATSPERB

Across TCGA patient cohorts, CATSPERB mutation is significantly associated with the total protein of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPERB-associated genes across cancer lineages are ASNS, p62 Lck ligand, and RBM15. Each is linked with CATSPERB in more than 4 cancer types. Because this analysis shows association rather than direction, both CATSPERB-to-partner and partner-to-CATSPERB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CATSPERB-low versus CATSPERB-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERB→partner) and Y-score (partner→CATSPERB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ASNS →	+0.486	+2.816	.047	.036	3	5
UCEC	p62 Lck ligand →	+0.449	+2.999	<.001	<.001	3	3
BLCA	RBM15 →	+0.484	+3.000	.036	.036	3	2
UCEC	14-3-3_beta →	-0.078	-2.195	.015	.009	3	2
UCEC	GAPDH →	+0.350	+1.874	.041	.049	3	2
UCEC	Notch1 →	+0.173	+2.058	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

ASNS by CATSPERB expression — LUSC

Explore this box plot interactively →