Across TCGA cell cohorts, CATSPER4 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CATSPER4-associated genes across cancer lineages are SLC10A2, IL25, and NLRP2B. Each is linked with CATSPER4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPER4-to-partner and partner-to-CATSPER4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER4→partner) and Y-score (partner→CATSPER4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SLC10A2 →	+0.006	+6.022	<.001	.001	3	1
CNS	IL25 →	+0.056	+3.459	<.001	.006	3	1
OVARY	NLRP2B →	+0.048	+4.392	.002	.004	3	1
LARGE_INTESTINE	OR12D3 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SLC17A3 →	+0.370	+3.707	<.001	.009	3	1
LARGE_INTESTINE	OPN5 →	+0.031	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

CATSPER4 survival (RNA) · tumor vs normal (RNA) · all CATSPER4 data types