CASTOR1

Across TCGA patient cohorts, CASTOR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,779 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CASTOR1-associated proteins across cancer lineages are TBC1D10A_S407, WDR91, and RPL12_S38. Each is linked with CASTOR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CASTOR1-to-partner and partner-to-CASTOR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASTOR1 versus TBC1D10A_S407 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASTOR1→partner) and Y-score (partner→CASTOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TBC1D10A_S407 →	+0.682	+0.480	.001	.006	3	4
OV	WDR91 →	+0.207	+0.241	.007	.005	3	3
LUAD	RPL12_S38 →	-0.938	-0.438	.002	.004	3	3
BRCA	SDC4 →	+0.578	+0.210	.001	.001	3	3
BRCA	KPNA2 →	-0.804	-0.286	<.001	<.001	3	3
BRCA	ABAT →	+1.073	+0.299	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,779 associations by consensus.

CASTOR1 vs TBC1D10A_S407 — GBM

Explore this scatter interactively →