CASP8AP2

Across TCGA cell cohorts, CASP8AP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,069 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CASP8AP2-associated GO terms across cancer lineages are Regulation of chromosome segregation, DNA replication, and DNA-templated DNA replication. Each is linked with CASP8AP2 in more than 19 cancer types. Because this analysis shows association rather than direction, both CASP8AP2-to-partner and partner-to-CASP8AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome segregation grouped by CASP8AP2-low versus CASP8AP2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP8AP2→partner) and Y-score (partner→CASP8AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of chromosome segregation →	+0.141	+1.446	<.001	<.001	3	20
OESOPHAGUS	DNA replication →	+0.148	+0.846	<.001	.002	3	20
BONE	DNA-templated DNA replication →	+0.174	+1.088	<.001	<.001	3	20
BONE	DNA recombination →	+0.114	+1.051	.001	<.001	3	20
BLOOD_Myeloma	Mitotic sister chromatid segregation →	+0.108	+0.960	<.001	<.001	3	20
LUNG_SCLC	Regulation of sister chromatid cohesion →	+0.132	+0.918	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,069 associations by consensus.

Regulation of chromosome segregation by CASP8AP2 expression — BLOOD_Myeloma

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