CASP5

Across TCGA patient cohorts, CASP5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,532 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CASP5-associated genes across cancer lineages are VAPA, MYL12A, and CEP76. Each is linked with CASP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CASP5-to-partner and partner-to-CASP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASP5 versus VAPA in COAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP5→partner) and Y-score (partner→CASP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VAPA →	+0.934	+0.573	<.001	.002	3	1
COAD	MYL12A →	+1.063	+0.523	.001	.007	3	1
COAD	CEP76 →	+0.628	+0.530	.003	.008	3	1
COAD	ACSBG1 →	+0.187	+0.379	<.001	.009	3	1
COAD	STEAP1B →	+0.262	+0.607	<.001	.007	3	1
COAD	STAG3L4 →	+0.608	+0.422	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,532 associations by consensus.

CASP5 vs VAPA — COAD

Explore this scatter interactively →