CASP2

Across TCGA patient cohorts, CASP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,362 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CASP2-associated proteins across cancer lineages are TNPO3, AAAS_S495, and NUP205. Each is linked with CASP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CASP2-to-partner and partner-to-CASP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASP2 versus TNPO3 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP2→partner) and Y-score (partner→CASP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TNPO3 →	+0.350	+0.497	<.001	<.001	3	7
PDAC	AAAS_S495 →	+0.895	+0.303	.001	<.001	3	6
GBM	NUP205 →	+0.218	+0.534	<.001	<.001	3	5
GBM	NUP93 →	+0.226	+0.520	<.001	<.001	3	5
LSCC	XPO1 →	+0.307	+0.611	<.001	<.001	3	5
GBM	ZC3HC1_S62 →	+0.549	+0.617	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,362 associations by consensus.

CASP2 vs TNPO3 — BRCA

Explore this scatter interactively →