CASP1P2

Across TCGA patient cohorts, CASP1P2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASP1P2-associated genes across cancer lineages are RNU4-58P, RNU6-1122P, and GSTA6P. Each is linked with CASP1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CASP1P2-to-partner and partner-to-CASP1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by CASP1P2-low versus CASP1P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASP1P2→partner) and Y-score (partner→CASP1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.654	+5.133	<.001	.008	3	1
UCEC	RNU6-1122P →	+1.012	+5.358	<.001	.006	3	1
UCEC	GSTA6P →	+0.212	+4.982	<.001	.009	3	1
UCEC	M6PRP1 →	+0.151	+5.358	<.001	.006	3	1
UCEC	RPS20P25 →	+0.420	+5.081	<.001	.008	3	1
UCEC	PDCL2P1 →	+0.327	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RNU4-58P by CASP1P2 expression — UCEC

Explore this box plot interactively →