CASD1

Across TCGA patient cohorts, CASD1 mutation is significantly associated with the RNA expression of many other genes, with 5,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CASD1-associated genes across cancer lineages are DNAJC8P1, FAM219B, and C3orf38. Each is linked with CASD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CASD1-to-partner and partner-to-CASD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJC8P1 grouped by CASD1-low versus CASD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CASD1→partner) and Y-score (partner→CASD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAJC8P1 →	+0.285	+1.895	<.001	.001	3	3
UCEC	FAM219B →	+0.534	+2.917	<.001	<.001	3	2
UCEC	C3orf38 →	+0.459	+3.595	<.001	.001	3	2
UCEC	ARF4P1 →	+0.346	+2.254	.004	.005	3	2
UCEC	RNA5SP412 →	+0.509	+1.645	<.001	.008	3	2
UCEC	SENP3-EIF4A1 →	+0.133	+3.006	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,341 associations by consensus.

DNAJC8P1 by CASD1 expression — UCEC

Explore this box plot interactively →