CASC22

Across TCGA patient cohorts, CASC22 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,376 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible CASC22-associated GO terms across cancer lineages are Peptidyl-lysine monomethylation, ATP synthesis coupled electron transport, and Negative regulation of miRNA processing. Each is linked with CASC22 in more than 6 cancer types. Because this analysis shows association rather than direction, both CASC22-to-partner and partner-to-CASC22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine monomethylation grouped by CASC22-low versus CASC22-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASC22→partner) and Y-score (partner→CASC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine monomethylation →	+0.076	+0.054	<.001	<.001	3	6
UCEC	ATP synthesis coupled electron transport →	+0.046	+0.030	<.001	<.001	3	6
READ	Negative regulation of miRNA processing →	+0.043	+0.014	.002	.006	2	6
UCEC	Positive regulation of DNA repair →	+0.033	+0.039	<.001	.001	3	5
STAD	Nucleoside triphosphate biosynthetic process →	+0.108	+0.065	<.001	<.001	2	6
STAD	Virion assembly →	+0.084	+0.052	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,376 associations by consensus.

Peptidyl-lysine monomethylation by CASC22 expression — STAD

Explore this box plot interactively →