CASC19

Across TCGA pan-cancer cohorts, CASC19 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CASC19 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CASC19 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CASC19 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

LUAD, KIRP, and DLBC are the cancer types where CASC19 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.682	0.845	<.001	147	view →
KIRP	OS	Median	All	0.587	0.782	<.001	105	view →
DLBC	DFS	Tertile	All	0.333	0.956	<.001	84	view →
OV	OS	Median	II,III,IV	0.373	0.274	.007	60	view →
UVM	DFS	Tertile	All	0.332	0.854	<.001	54	view →
ACC	OS	Tertile	II,III,IV	0.126	0.682	.001	45	view →
PAAD	OS	Tertile	All	0.295	0.591	<.001	40	view →
COAD	DFS	Quartile	III,IV	0.484	0.725	.003	33	view →
LIHC	OS	Quartile	All	0.718	0.871	.003	26	view →
UCS	DFS	Tertile	All	0.152	0.480	.001	24	view →
SKCM	DFS	Quartile	IV	0.086	0.540	.001	19	view →
THYM	DFS	Tertile	III,IV	0.428	1.000	.002	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CASC19–LUAD (OS)

Open the LUAD breakdown →