CASC19

Across TCGA pan-cancer cohorts, CASC19 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CASC19’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CASC19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CASC19 is over-expressed in tumor.

COAD, STAD, and READ are the cancer types where CASC19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CASC19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+2.521	<.001	11	view →
STAD	Male	All	+0.982	<.001	8	view →
READ	All	All	+2.582	<.001	7	view →
LUSC	Female	All	+1.869	<.001	7	view →
KIRP	All	II,III,IV	+0.860	.012	6	view →
HNSC	Male	IV	+1.958	.006	4	view →
LUAD	All	All	+0.650	.002	4	view →
LIHC	Male	III,IV	+0.957	.015	3	view →
KIRC	Male	All	+0.225	.011	3	view →
PRAD	All	All	+0.264	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CASC19–COAD

Open the COAD breakdown →