CASC16

Across TCGA patient cohorts, CASC16 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,715 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CASC16-associated GO terms across cancer lineages are Vesicle budding from membrane, Protein N-linked glycosylation, and Digestive system process. Each is linked with CASC16 in more than 12 cancer types. Because this analysis shows association rather than direction, both CASC16-to-partner and partner-to-CASC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by CASC16-low versus CASC16-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CASC16→partner) and Y-score (partner→CASC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Vesicle budding from membrane →	+0.062	+0.185	<.001	<.001	2	13
ESCA	Protein N-linked glycosylation →	+0.065	+0.259	<.001	<.001	3	11
ESCA	Digestive system process →	+0.080	+0.278	<.001	<.001	3	11
ESCA	Regulation of Golgi to plasma membrane protein transport →	+0.091	+0.228	<.001	<.001	3	11
PCPG	Translational elongation →	+0.028	+0.098	<.001	<.001	3	10
STAD	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.061	+0.179	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,715 associations by consensus.

Vesicle budding from membrane by CASC16 expression — ESCA

Explore this box plot interactively →