CASC15

Across TCGA patient cohorts, CASC15 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,785 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CASC15-associated proteins across cancer lineages are CTHRC1, DENND2D, and ANTXR1. Each is linked with CASC15 in more than 8 cancer types. Because this analysis shows association rather than direction, both CASC15-to-partner and partner-to-CASC15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASC15 versus CTHRC1 in OV, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASC15→partner) and Y-score (partner→CASC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CTHRC1 →	+1.128	+0.413	<.001	<.001	3	9
OV	DENND2D →	-0.480	-0.246	.005	.008	3	9
OV	ANTXR1 →	+0.709	+0.416	<.001	<.001	3	9
BRCA	ANGPTL2 →	+0.814	+0.645	<.001	<.001	3	9
OV	AEBP1 →	+0.875	+0.418	<.001	<.001	3	8
HNSC	CEP170 →	+0.273	+0.969	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,785 associations by consensus.

CASC15 vs CTHRC1 — OV

Explore this scatter interactively →