CARTPT

Across TCGA cell cohorts, CARTPT RNA expression is significantly associated with the go_rna of many other GO terms, with 145 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CARTPT-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Type III interferon-mediated signaling pathway, and Microtubule severing. Each is linked with CARTPT in more than 2 cancer types. Because this analysis shows association rather than direction, both CARTPT-to-partner and partner-to-CARTPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by CARTPT-low versus CARTPT-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARTPT→partner) and Y-score (partner→CARTPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.073	+0.019	.007	.006	3	3
SKIN	Type III interferon-mediated signaling pathway →	+0.160	+0.012	.002	.007	3	2
SKIN	Microtubule severing →	+0.058	+0.013	.001	.005	3	2
SKIN	Glucosamine metabolic process →	+0.129	+0.013	<.001	.005	3	2
SKIN	Cellular response to type III interferon →	+0.160	+0.012	.002	.007	3	2
SKIN	Lysosome to ER cholesterol transport →	-0.125	-0.012	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by CARTPT expression — SKIN

Explore this box plot interactively →