CARTPT

Across TCGA pan-cancer cohorts, CARTPT RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CARTPT data layer compared with 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CARTPT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CARTPT expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LIHC, and MESO are the cancer types where CARTPT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.773	0.653	.005	106	view →
LIHC	OS	Tertile	All	0.224	0.542	<.001	69	view →
MESO	OS	Tertile	II,III,IV	0.259	0.628	.008	54	view →
LUAD	DFS	Tertile	II,III,IV	0.563	0.200	.006	51	view →
UVM	DFS	Tertile	All	0.411	0.828	.003	39	view →
UCEC	DFS	Median	All	0.590	0.689	.001	34	view →
SKCM	OS	Tertile	All	1.000	0.845	.005	30	view →
KICH	OS	Tertile	All	0.683	0.941	.004	24	view →
THYM	DFS	Tertile	II,III,IV	0.544	0.830	.021	20	view →
READ	DFS	Median	II,III,IV	0.338	0.854	.001	19	view →
KIRP	DFS	Tertile	III,IV	0.936	0.636	.025	15	view →
STAD	DFS	Quartile	All	0.572	0.810	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CARTPT–HNSC (DFS)

Open the HNSC breakdown →