CARNS1

Across TCGA patient cohorts, CARNS1 mutation is significantly associated with the RNA expression of many other genes, with 1,310 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CARNS1-associated genes across cancer lineages are NF1P11, MIR655, and LINC02676. Each is linked with CARNS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CARNS1-to-partner and partner-to-CARNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF1P11 grouped by CARNS1-low versus CARNS1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARNS1→partner) and Y-score (partner→CARNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NF1P11 →	+0.083	+4.605	<.001	.001	3	2
LUAD	MIR655 →	+0.617	+7.930	<.001	.008	3	2
COAD	LINC02676 →	+0.226	+7.741	<.001	.009	3	2
COAD	MIR3689B →	+0.273	+7.741	<.001	.009	3	2
COAD	MIR4535 →	+0.551	+7.741	<.001	.009	3	2
CESC	RNA5SP447 →	+0.349	+5.201	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,310 associations by consensus.

NF1P11 by CARNS1 expression — BRCA

Explore this box plot interactively →