CARNMT1

Across TCGA patient cohorts, CARNMT1 mutation is significantly associated with the RNA expression of many other genes, with 1,480 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CARNMT1-associated genes across cancer lineages are RN7SL248P, RNU2-47P, and RNA5SP222. Each is linked with CARNMT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CARNMT1-to-partner and partner-to-CARNMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CARNMT1-low versus CARNMT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARNMT1→partner) and Y-score (partner→CARNMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.054	+3.059	<.001	.005	3	3
BRCA	RNU2-47P →	+0.628	+8.055	<.001	.007	3	2
BRCA	RNA5SP222 →	+0.286	+7.731	<.001	.009	3	2
UCEC	SNRPCP20 →	+0.156	+1.949	.004	.005	3	2
UCEC	PEBP1P3 →	+0.171	+2.094	.006	<.001	3	2
READ	PGBD4P2 →	+0.121	+5.257	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,480 associations by consensus.

RN7SL248P by CARNMT1 expression — UCEC

Explore this box plot interactively →