CARMIL1

Across TCGA cell cohorts, CARMIL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,065 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CARMIL1-associated GO terms across cancer lineages are Negative regulation of barbed-end actin filament capping, Actin filament-based transport, and Macropinocytosis. Each is linked with CARMIL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CARMIL1-to-partner and partner-to-CARMIL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of barbed-end actin filament capping grouped by CARMIL1-low versus CARMIL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARMIL1→partner) and Y-score (partner→CARMIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of barbed-end actin filament capping →	+0.719	+0.939	.007	<.001	3	13
LUNG_SCLC	Actin filament-based transport →	+0.142	+1.097	<.001	<.001	3	12
OVARY	Macropinocytosis →	+0.164	+1.386	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Regulation of heart rate by cardiac conduction →	+0.116	+0.720	.007	<.001	2	12
STOMACH	Actin filament network formation →	+0.122	+0.953	<.001	<.001	3	10
STOMACH	Cardiac conduction →	+0.172	+0.994	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,065 associations by consensus.

Negative regulation of barbed-end actin filament capping by CARMIL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →