Across TCGA patient cohorts, CARD11 protein abundance is significantly associated with the RNA expression of many other genes, with 10,316 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CARD11-associated genes across cancer lineages are RASAL3, CD33, and CD4. Each is linked with CARD11 in more than 7 cancer types. Because this analysis shows association rather than direction, both CARD11-to-partner and partner-to-CARD11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD11→partner) and Y-score (partner→CARD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RASAL3 →	+0.989	+0.624	<.001	<.001	3	8
GBM	CD33 →	+0.824	+0.450	<.001	<.001	3	8
UCEC	CD4 →	+1.121	+0.596	<.001	<.001	3	8
UCEC	GIMAP2 →	+1.008	+0.483	.002	<.001	3	8
OV	SLC15A3 →	+0.985	+0.467	.001	.004	3	8
UCEC	CD86 →	+1.122	+0.624	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,316 associations by consensus.

Exploration

CARD11 survival (RNA) · tumor vs normal (RNA) · all CARD11 data types