Across TCGA cell cohorts, CARD11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,015 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CARD11-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Cellular response to abiotic stimulus, and Arp2/3 complex-mediated actin nucleation. Each is linked with CARD11 in more than 8 cancer types. Because this analysis shows association rather than direction, both CARD11-to-partner and partner-to-CARD11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD11→partner) and Y-score (partner→CARD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cellular response to environmental stimulus →	+0.022	+1.336	.002	.003	3	9
PANCREAS	Cellular response to abiotic stimulus →	+0.022	+1.336	.002	.003	3	9
STOMACH	Arp2/3 complex-mediated actin nucleation →	+0.080	+2.065	.003	.004	3	9
LUNG_NSCLC_LUAD	Hepatocyte growth factor receptor signaling pathway →	+0.134	+1.475	<.001	.001	3	9
LUNG_NSCLC_LUAD	Cellular hyperosmotic response →	+0.082	+1.371	<.001	.002	3	8
PANCREAS	Regulation of transferase activity →	+0.048	+1.590	<.001	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,015 associations by consensus.

Exploration

CARD11 survival (RNA) · tumor vs normal (RNA) · all CARD11 data types