CARD10

Across TCGA patient cohorts, CARD10 protein abundance is significantly associated with the RNA expression of many other genes, with 12,214 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CARD10-associated genes across cancer lineages are PTPRN2, ZG16B, and SATL1. Each is linked with CARD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both CARD10-to-partner and partner-to-CARD10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD10 versus PTPRN2 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD10→partner) and Y-score (partner→CARD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPRN2 →	+1.901	+0.384	<.001	.002	3	2
LUAD	ZG16B →	+1.159	+0.259	<.001	.001	3	2
BRCA	SATL1 →	-0.102	-0.371	.008	.009	3	2
LUAD	NRAP →	+0.218	+0.228	.005	.007	2	3
PDAC	CYP1B1-AS1 →	-0.497	-0.326	.004	.003	3	2
LSCC	PAXBP1-AS1 →	-0.268	-0.372	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,214 associations by consensus.

CARD10 vs PTPRN2 — BRCA

Explore this scatter interactively →