CARD10

Across TCGA cell cohorts, CARD10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,001 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CARD10-associated GO terms across cancer lineages are Regulation of actin filament organization, Membrane raft organization, and Epithelial cell development. Each is linked with CARD10 in more than 11 cancer types. Because this analysis shows association rather than direction, both CARD10-to-partner and partner-to-CARD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by CARD10-low versus CARD10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD10→partner) and Y-score (partner→CARD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of actin filament organization →	+0.072	+2.606	<.001	<.001	3	12
BONE	Membrane raft organization →	+0.176	+2.350	<.001	<.001	3	12
BONE	Epithelial cell development →	+0.116	+2.572	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of fibroblast proliferation →	+0.101	+1.789	.001	.004	3	11
BREAST	Caveola assembly →	+0.222	+1.546	<.001	<.001	3	11
SOFT_TISSUE	Membrane raft assembly →	+0.141	+1.525	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,001 associations by consensus.

Regulation of actin filament organization by CARD10 expression — BONE

Explore this box plot interactively →