CAPZB

Across TCGA cell cohorts, CAPZB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,454 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CAPZB-associated GO terms across cancer lineages are Regulation of type 2 mitophagy, Protein import into peroxisome membrane, and Mitochondrion to lysosome vesicle-mediated transport. Each is linked with CAPZB in more than 11 cancer types. Because this analysis shows association rather than direction, both CAPZB-to-partner and partner-to-CAPZB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of type 2 mitophagy grouped by CAPZB-low versus CAPZB-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZB→partner) and Y-score (partner→CAPZB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of type 2 mitophagy →	+0.147	+0.756	<.001	.004	3	11
OESOPHAGUS	Protein import into peroxisome membrane →	+0.159	+0.811	.001	.003	3	11
LUNG_NSCLC_LUSC	Mitochondrion to lysosome vesicle-mediated transport →	+0.261	+0.936	.006	.002	1	12
LUNG_NSCLC_LUSC	Mitochondrion-derived vesicle mediated transport →	+0.261	+0.936	.006	.002	1	12
URINARY_TRACT	Positive regulation of type 2 mitophagy →	+0.115	+0.718	<.001	.001	3	10
BONE	Integrin-mediated signaling pathway →	+0.270	+0.788	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,454 associations by consensus.

Regulation of type 2 mitophagy by CAPZB expression — URINARY_TRACT

Explore this box plot interactively →