CAPSL

Across TCGA patient cohorts, CAPSL protein abundance is significantly associated with the RNA expression of many other genes, with 1,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPSL-associated genes across cancer lineages are SPEF1, RP1, and CCDC114. Each is linked with CAPSL in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPSL-to-partner and partner-to-CAPSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPSL versus SPEF1 in UCEC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPSL→partner) and Y-score (partner→CAPSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+2.333	+1.450	<.001	<.001	3	3
UCEC	RP1 →	+1.356	+0.941	<.001	<.001	3	3
UCEC	CCDC114 →	+1.535	+0.831	<.001	<.001	3	3
UCEC	RSPH4A →	+1.803	+0.948	<.001	<.001	3	3
UCEC	C6orf118 →	+2.079	+1.050	<.001	<.001	3	3
LUAD	NME5 →	+1.188	+0.785	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,812 associations by consensus.

CAPSL vs SPEF1 — UCEC

Explore this scatter interactively →