CAPNS1

Across TCGA patient cohorts, CAPNS1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,305 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPNS1-associated genes across cancer lineages are KNTC1, CDC6, and AHNAK. Each is linked with CAPNS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPNS1-to-partner and partner-to-CAPNS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPNS1 versus KNTC1 in LSCC, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPNS1→partner) and Y-score (partner→CAPNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KNTC1 →	-0.644	-0.233	<.001	<.001	3	7
UCEC	CDC6 →	-0.986	-0.261	<.001	.003	3	7
GBM	AHNAK →	+0.943	+0.390	<.001	<.001	3	7
BRCA	CAPN2 →	+0.862	+0.323	<.001	<.001	3	7
GBM	LMNB1 →	-0.944	-0.322	<.001	<.001	3	6
GBM	NCAPH →	-0.864	-0.268	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,305 associations by consensus.

CAPNS1 vs KNTC1 — LSCC

Explore this scatter interactively →