CAPN3

Across TCGA patient cohorts, CAPN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,653 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAPN3-associated proteins across cancer lineages are YBX1, TTI1, and DNMT1_S127. Each is linked with CAPN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPN3-to-partner and partner-to-CAPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN3 versus YBX1 in BRCA, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN3→partner) and Y-score (partner→CAPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YBX1 →	-0.305	-0.306	.001	.004	3	7
GBM	TTI1 →	-0.297	-0.742	<.001	<.001	3	6
BRCA	DNMT1_S127 →	-0.707	-0.414	<.001	<.001	3	6
BRCA	SLIRP →	-0.581	-0.577	<.001	<.001	3	6
LSCC	CHTF18_S871 →	-0.796	-0.647	<.001	<.001	3	6
OV	EZH2_T367 →	-1.412	-0.415	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,653 associations by consensus.

CAPN3 vs YBX1 — BRCA

Explore this scatter interactively →