CAPN2

Across TCGA patient cohorts, CAPN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,485 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CAPN2-associated proteins across cancer lineages are TNKS1BP1, CAPNS1, and TNKS1BP1_S836. Each is linked with CAPN2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CAPN2-to-partner and partner-to-CAPN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN2 versus TNKS1BP1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN2→partner) and Y-score (partner→CAPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TNKS1BP1 →	+0.261	+0.781	<.001	.002	3	7
GBM	CAPNS1 →	+0.375	+0.587	<.001	<.001	3	7
LUAD	TNKS1BP1_S836 →	+0.618	+0.654	<.001	<.001	3	6
LSCC	S100A16 →	+0.528	+0.432	<.001	<.001	3	6
LUAD	C1orf116 →	+0.876	+0.876	<.001	<.001	3	5
BRCA	C1orf116_T456 →	+1.206	+0.876	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,485 associations by consensus.

CAPN2 vs TNKS1BP1 — BRCA

Explore this scatter interactively →