CAPN2

Across TCGA patient cohorts, CAPN2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,605 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN2-associated genes across cancer lineages are SSPN, LMOD1, and LRRN4CL. Each is linked with CAPN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CAPN2-to-partner and partner-to-CAPN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN2 versus SSPN in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN2→partner) and Y-score (partner→CAPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SSPN →	+0.968	+0.461	<.001	<.001	3	9
OV	LMOD1 →	+1.212	+0.599	<.001	<.001	3	9
BRCA	LRRN4CL →	+1.003	+0.392	<.001	<.001	3	9
LUAD	NCAPH →	-0.895	-0.476	<.001	<.001	3	7
COAD	ABCA8 →	+1.051	+0.328	<.001	<.001	3	7
UCEC	ABCA9 →	+1.031	+0.423	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,605 associations by consensus.

CAPN2 vs SSPN — BRCA

Explore this scatter interactively →