CAPN2

Across TCGA patient cohorts, CAPN2 mutation is significantly associated with the RNA expression of many other genes, with 3,467 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPN2-associated genes across cancer lineages are MIR4307HG, RNU6-543P, and MIR7-3. Each is linked with CAPN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPN2-to-partner and partner-to-CAPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4307HG grouped by CAPN2-low versus CAPN2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN2→partner) and Y-score (partner→CAPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR4307HG →	+0.105	+4.575	<.001	.001	3	3
BRCA	RNU6-543P →	+0.210	+7.055	<.001	<.001	3	3
CESC	MIR7-3 →	+0.370	+6.342	<.001	.001	3	2
CESC	DNMT3AP1 →	+0.030	+5.418	<.001	.005	3	2
PRAD	LINC01784 →	+0.104	+7.939	<.001	.008	3	2
READ	RNU6-178P →	+0.578	+4.361	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,467 associations by consensus.

MIR4307HG by CAPN2 expression — BRCA

Explore this box plot interactively →