CAPN15

Across TCGA patient cohorts, CAPN15 protein abundance is significantly associated with the RNA expression of many other genes, with 15,745 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN15-associated genes across cancer lineages are GDF11, MLLT11, and ADAM23. Each is linked with CAPN15 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAPN15-to-partner and partner-to-CAPN15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN15 versus GDF11 in LSCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN15→partner) and Y-score (partner→CAPN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GDF11 →	-0.543	-0.176	<.001	.002	3	4
HNSC	MLLT11 →	-0.834	-0.186	.006	.002	3	4
LSCC	ADAM23 →	-1.353	-0.134	.001	.004	3	4
LSCC	RND2 →	-0.888	-0.204	<.001	<.001	3	3
COAD	F13A1 →	-1.569	-0.519	<.001	<.001	3	3
LSCC	CDH8 →	-0.465	-0.144	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,745 associations by consensus.

CAPN15 vs GDF11 — LSCC

Explore this scatter interactively →