CAPN10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CAPN10 protein abundance is significantly associated with the RNA expression of many other genes, with 646 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPN10-associated genes across cancer lineages are MAP1B, PLA2G3, and ST8SIA5. Each is linked with CAPN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAPN10-to-partner and partner-to-CAPN10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN10 versus MAP1B in CCRCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN10→partner) and Y-score (partner→CAPN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCMAP1B →+1.551+0.645.009.00432
GBMPLA2G3 →-0.164-0.497.003.00631
GBMST8SIA5 →-1.885-0.574<.001<.00131
GBMUBL4A →-0.447-0.581.003.00131
GBMSLC25A15 →-0.479-0.508<.001.00131
GBMFAM189A1 →-0.851-0.379.004.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 646 associations by consensus.

CAPN10 vs MAP1B — CCRCC

Per-sample scatter of CAPN10 vs MAP1B in CCRCC (Pearson r = 0.70).

Explore this scatter interactively →

Exploration