CANX

Across TCGA patient cohorts, CANX RNA expression is significantly associated with the protein abundance of many other proteins, with 10,762 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CANX-associated proteins across cancer lineages are NPM1, CANX_S583, and GEMIN5. Each is linked with CANX in more than 5 cancer types. Because this analysis shows association rather than direction, both CANX-to-partner and partner-to-CANX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CANX versus NPM1 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CANX→partner) and Y-score (partner→CANX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NPM1 →	+0.353	+0.482	<.001	<.001	3	6
BRCA	CANX_S583 →	+0.611	+0.536	<.001	<.001	3	6
LUAD	GEMIN5 →	+0.229	+0.519	<.001	<.001	3	6
OV	TTC1 →	+0.296	+0.650	<.001	<.001	3	5
CCRCC	YTHDC2 →	+0.289	+0.450	<.001	<.001	3	5
OV	FAF2 →	+0.310	+0.754	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,762 associations by consensus.

CANX vs NPM1 — OV

Explore this scatter interactively →