CANX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CANX protein abundance is significantly associated with the RNA expression of many other genes, with 9,248 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CANX-associated genes across cancer lineages are HSPA9, LMAN2, and DDX41. Each is linked with CANX in more than 4 cancer types. Because this analysis shows association rather than direction, both CANX-to-partner and partner-to-CANX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CANX versus HSPA9 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CANX→partner) and Y-score (partner→CANX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADHSPA9 →+0.464+0.428<.001<.00135
OVLMAN2 →+0.655+0.369<.001<.00135
OVDDX41 →+0.663+0.534<.001<.00135
OVTMED9 →+0.820+0.480<.001<.00135
GBMPPP1R16B →-0.906-0.211<.001<.00134
OVFAF2 →+0.488+0.367<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,248 associations by consensus.

CANX vs HSPA9 — LUAD

Per-sample scatter of CANX vs HSPA9 in LUAD (Pearson r = 0.29).

Explore this scatter interactively →

Exploration