CANX

Across TCGA patient cohorts, CANX mutation is significantly associated with the RNA expression of many other genes, with 1,705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CANX-associated genes across cancer lineages are CTAG1B, CTAG1A, and LINC01046. Each is linked with CANX in more than 2 cancer types. Because this analysis shows association rather than direction, both CANX-to-partner and partner-to-CANX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTAG1B grouped by CANX-low versus CANX-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CANX→partner) and Y-score (partner→CANX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CTAG1B →	+0.138	+4.984	<.001	.005	3	3
HNSC	CTAG1A →	+0.116	+5.124	<.001	.008	3	3
SKCM	LINC01046 →	+0.100	+4.302	.001	.002	3	3
UCEC	PHF5A →	+0.402	+2.471	.002	.001	3	2
UCEC	ZNF207 →	+0.308	+2.040	.008	.005	3	2
UCEC	BCCIP →	+0.345	+2.081	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,705 associations by consensus.

CTAG1B by CANX expression — LUAD

Explore this box plot interactively →