CANX

Across TCGA cell cohorts, CANX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,177 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CANX-associated GO terms across cancer lineages are Protein exit from endoplasmic reticulum, Multi-pass transmembrane protein insertion into ER membrane, and Endoplasmic reticulum to cytosol transport. Each is linked with CANX in more than 15 cancer types. Because this analysis shows association rather than direction, both CANX-to-partner and partner-to-CANX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein exit from endoplasmic reticulum grouped by CANX-low versus CANX-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CANX→partner) and Y-score (partner→CANX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein exit from endoplasmic reticulum →	+0.122	+0.826	.003	.001	3	16
LUNG_SCLC	Multi-pass transmembrane protein insertion into ER membrane →	+0.136	+0.886	<.001	<.001	3	14
BLOOD_Myeloma	Endoplasmic reticulum to cytosol transport →	+0.144	+0.857	.001	.004	2	15
BLOOD_Myeloma	Retrograde protein transport, ER to cytosol →	+0.144	+0.857	.001	.004	2	15
SOFT_TISSUE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.147	+0.956	<.001	<.001	3	13
BLOOD_Lymphoma	Protein insertion into ER membrane →	+0.081	+1.009	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,177 associations by consensus.

Protein exit from endoplasmic reticulum by CANX expression — LUNG_SCLC

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