CAND2

Across TCGA cell cohorts, CAND2 mutation is significantly associated with the RNA expression of many other genes, with 766 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAND2-associated genes across cancer lineages are C1orf185, PLSCR5, and OR6K3. Each is linked with CAND2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAND2-to-partner and partner-to-CAND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf185 grouped by CAND2-low versus CAND2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND2→partner) and Y-score (partner→CAND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	C1orf185 →	+0.097	+4.584	<.001	.002	3	1
URINARY_TRACT	PLSCR5 →	+0.022	+4.087	<.001	.009	3	1
OESOPHAGUS	OR6K3 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	CENPVL3 →	+0.703	+4.906	<.001	.006	3	1
OESOPHAGUS	TAS2R39 →	+0.043	+4.906	<.001	.006	3	1
BREAST	PAGE3 →	+0.042	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 766 associations by consensus.

C1orf185 by CAND2 expression — URINARY_TRACT

Explore this box plot interactively →