CAMTA1

Across TCGA patient cohorts, CAMTA1 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMTA1-associated genes across cancer lineages are 4E-BP1, JNK_pT183_Y185, and FOXO3a. Each is linked with CAMTA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAMTA1-to-partner and partner-to-CAMTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by CAMTA1-low versus CAMTA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMTA1→partner) and Y-score (partner→CAMTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.249	+1.256	<.001	<.001	3	4
UCEC	JNK_pT183_Y185 →	-0.080	-1.106	.045	.017	3	4
COAD	FOXO3a →	-0.099	-1.794	.038	.024	3	3
COAD	Notch1 →	+0.162	+2.584	.007	.009	3	3
COAD	Chk2_pT68 →	-0.127	-2.305	.017	.032	3	3
SKCM	eEF2 →	+0.282	+1.584	.012	.016	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

4E-BP1 by CAMTA1 expression — UCEC

Explore this box plot interactively →